The impact of hypoxia and reactive oxygen species (ROS) in anti-tumor immunity: mechanisms of action and therapeutic opportunities
Dr. Asis Palazon
Fecha: 12-12-2022
Hora: 12 h
Lugar: Aula A.06 del edificio Ada Byron
Dr. Asis Palazon leads the Cancer Immunology and Immunotherapy lab at CIC bioGUNE since 2019. Research in the lab is focused on the study of the features of the tumor microenvironment (TME) that influence immune responses. In solid tumors, these include limited oxygen supply (hypoxia) and the accumulation of reactive oxygen species (ROS) that modulate the optimal function of cytotoxic T lymphocytes. Understanding these mechanisms will help to develop differentiated approaches to cancer immunotherapy, including monoclonal antibodies and cell therapies. Before joining CIC bioGUNE, Dr. A Palazon was a senior scientist at AstraZeneca-Medimmune and a postdoctoral researcher at University of Cambridge (UK).
Abstract
The world is becoming unprecedentedly connected thanks to emerging media and cloud-based technologies. The holy grail of metaverse requires recreating a remotely shared world as a digital twin of the physical planet. In this world, the human is probably the most complex mechanical, physical, and biological system. Unlike computers, it is remarkably challenging to model and engineer how humans perceive and react in a virtual environment. By leveraging computational advancements such as machine learning and biometric sensors, this talk will share some recent research on altering and optimizing the human visual and behavioral perception toward creating the ultimate metaverse.
Bio
Qi Sun is an assistant professor at New York University, Tandon School of Engineering (joint with Dept. of Computer Science and Engineering and Center for Urban Science and Progress). Before joining NYU, he was a research scientist at Adobe Research and a research intern at NVIDIA Research. He received his Ph.D. at Stony Brook University. His research interests lie in computer graphics, VR/AR, vision science, machine learning, and human-computer interaction. He is a recipient of the IEEE Virtual Reality Best Dissertation Award.